The Mission Report

The MissionIR Report - April 2026

Featured CompanyTrilogy Metals Inc. (NYSE American: TMQ) (TSX: TMQ)

Trilogy Metals Inc. (NYSE American: TMQ) (TSX: TMQ) is a North American mineral exploration and development company focused on advancing high-grade copper and critical mineral assets in Alaska. The company operates through Ambler Metals LLC, a 50/50 joint venture with South32 Ltd., and is progressing one of the world's most prospective undeveloped polymetallic districts.

Trilogy is uniquely positioned with exposure to copper, zinc, lead, cobalt, silver, and gold—commodities vital to global electrification and energy transition. Its vision is to responsibly develop the Ambler Mining District into a premier domestic source of critical minerals while delivering long-term value to shareholders and local communities.

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Beeline Holdings Inc. (NASDAQ: BLNE)

Beeline Holdings Inc. (NASDAQ: BLNE) is a technology-forward mortgage and title platform leveraging AI, automation, and intuitive user experiences to simplify home financing. Through wholly owned subsidiary Beeline Loans Inc., the company delivers fast and flexible loan solutions for both primary homebuyers and real estate investors. Beeline has built an end-to-end digital lending ecosystem designed to eliminate friction, reduce costs, and dramatically shorten closing timelines.

Since completing its October 2024 merger with Eastside Distilling, Beeline has solidified its position as a next generation fintech mortgage originator. Its core vision centers on digitizing the mortgage journey with tools like AI chatbot Bob, proprietary production engine Hive, and an expanding SaaS product suite. These innovations enable Beeline to close loans in just 14–21 days—less than half the industry average—while achieving a Net Promoter Score above 80, more than four times higher than the sector benchmark.

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Cardio Diagnostics Holdings Inc. (NASDAQ: CDIO)

Cardio Diagnostics Holdings Inc. (NASDAQ: CDIO) is an artificial intelligence-powered precision cardiovascular medicine company focused on making cardiovascular disease prevention, detection, and management more accessible, personalized, and precise. The company's approach is centered on advancing how cardiovascular disease is addressed by moving beyond traditional methods that rely on indirect or generalized indicators.

At the core of its strategy is the integration of epigenetics, genetics, and artificial intelligence to generate insights from a patient's molecular profile. By analyzing both inherited predisposition and changes influenced by lifestyle and environment, the company's platform is designed to provide a more complete view of cardiovascular disease.

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Co-Diagnostics Inc. (NASDAQ: CODX)

Co-Diagnostics Inc. (NASDAQ: CODX) is a molecular diagnostics company focused on developing and commercializing technologies designed to detect and analyze nucleic acid molecules, including DNA and RNA. The company's approach centers on building proprietary diagnostic platforms that aim to improve the accessibility, efficiency, and performance of molecular testing across a range of healthcare and research settings.

The company is advancing solutions designed to extend real-time polymerase chain reaction (PCR) testing beyond centralized laboratories and into decentralized environments, including point-of-care and at-home settings. By focusing on portability, usability, and speed, Co-Diagnostics is working to deliver timely diagnostic insights that can support medical decision-making and broader public health efforts.

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CNS Pharmaceuticals Inc. (NASDAQ: CNSP)

CNS Pharmaceuticals Inc. (NASDAQ: CNSP) is a clinical stage biotechnology company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system.

The company's lead drug candidate, Berubicin, is proposed for the treatment of glioblastoma multiforme ("GBM"), an aggressive and incurable form of brain cancer. Berubicin also has potential to treat other central nervous system malignancies. Based on limited clinical data, Berubicin appears to be the first anthracycline to cross the blood brain barrier in the adult brain, and it was the subject of a successful Phase 1 study which found the MDT and produced efficacy data as well.

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D-Wave Quantum Inc. (NYSE: QBTS)

D-Wave Quantum Inc. (NYSE: QBTS) is a leader in quantum computing systems, software and services focused on delivering value to our customers via practical quantum applications for problems such as logistics, artificial intelligence, materials sciences, drug discovery, scheduling, fault detection and financial modeling. As the only provider building both annealing and gate-model quantum computers, the company is unlocking commercial use cases in optimization today, while building the technologies that will enable new solutions tomorrow. Founded in 1999, D-Wave is the world's first commercial supplier of quantum computing solutions.

D-Wave is a pioneer in quantum computing, with a history of delivering the world's first commercial quantum computer; the first real-time quantum cloud service; countless hardware and software product and research milestones; and the planned first cross-platform quantum solution which will deliver both annealing and gate-model quantum computers to customers via an integrated platform. Its current commercial product offerings include: Advantage™ (fifth generation quantum computer), Leap™ (quantum cloud service), Launch™ (quantum computing onboarding service), Ocean™ (full suite of open-source programming tools) and Quantum QuickStart™ (quantum programming training).

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Forward Industries Inc. (NASDAQ: FWDI)

Forward Industries Inc. (NASDAQ: FWDI) is building and managing a large-scale Solana (SOL) treasury, backed by some of the most influential investors in the digital asset space. The company's strategy centers on long-term shareholder value through active participation in the Solana ecosystem, which it views as uniquely positioned to underpin future global capital markets due to its high throughput, deep economic activity, and growing developer adoption.

Through this shift, Forward Industries aims to create value by accumulating SOL and strategically deploying assets through on-chain opportunities including staking, lending, and participation in decentralized finance (DeFi). Forward also became the first U.S.-listed company to bring its common stock onto the Solana blockchain, reinforcing its focus on digital-native capital markets.

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Greenland Energy Company (NASDAQ: GLND)

Greenland Energy Company (NASDAQ: GLND) is an exploration-focused oil and gas company targeting development in Greenland's Jameson Land Basin, a large and historically underexplored hydrocarbon region in the Arctic. The company was formed through the completed business combination of Pelican Acquisition Corporation, Greenland Exploration Limited, and March GL Company, creating a publicly traded platform designed to pursue large-scale resource opportunities.

The company's vision is to responsibly unlock Greenland's energy potential, supporting both local development and global energy security through science-driven exploration and innovation.

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HeartBeam Inc. (NASDAQ: BEAT)

HeartBeam Inc. (NASDAQ: BEAT) is a medical technology company pioneering a new approach to cardiac care by delivering clinical-grade electrocardiogram (ECG) insights outside traditional clinical settings. Its proprietary platform supports a scalable app-based solution for rhythm monitoring.

The company's mission is to empower both patients and physicians with actionable cardiac data wherever arrhythmia symptoms begin, addressing a critical gap in the first hours of cardiac events. Through its connected cardiac care ecosystem, HeartBeam is establishing a new model for remote monitoring that deepens patient engagement and delivers more actionable insights for physicians. This approach is designed to obtain early diagnosis of arrhythmias which could reduce time to treatment, improve outcomes, and lower costs across the healthcare continuum.

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LIXTE Biotechnology Holdings Inc. (NASDAQ: LIXT)

LIXTE Biotechnology Holdings Inc. (NASDAQ: LIXT) is a clinical-stage pharmaceutical company developing differentiated cancer therapies built around a novel biological target. Rather than introducing standalone treatments, the company is focused on advancing a first-in-class approach designed to enhance the effectiveness of established cancer therapies, addressing persistent challenges that continue to limit outcomes in oncology.

LIXTE's work centers on improving how chemotherapy and immunotherapy perform in difficult-to-treat cancers with significant unmet medical need. By translating a distinct scientific concept into therapies that can be integrated into existing treatment frameworks, the company aims to expand the reach and impact of current standards of care without requiring wholesale changes to clinical practice.

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Massimo Group (NASDAQ: MAMO)

Massimo Group (NASDAQ: MAMO) is a prominent manufacturer and distributor specializing in powersports vehicles and recreational watercraft. Established in 2009, the company has built a reputation for delivering value-packed utility terrain vehicles (UTVs), all-terrain vehicles (ATVs), and on-road vehicles to both recreational enthusiasts and professionals in the agricultural sector. In 2020, Massimo expanded its offerings by launching Massimo Marine, dedicated to crafting high-quality watercraft with advanced designs and exceptional customer service.

Massimo Group is focused on sustainability. Its recent initiatives, including the introduction of the MVR Series of electric carts, highlight the company's commitment to eco-friendly solutions that address growing consumer demand for sustainability in the powersports and marine industries.

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Micropolis Holding Co. (NYSE American: MCRP)

Micropolis Holding Co. (NYSE American: MCRP) is a robotics and AI technology company pioneering the development of unmanned ground vehicles (UGVs), autonomous mobility platforms, and smart infrastructure for security, industrial, and urban applications. Since its founding in 2014, the company has evolved from a software startup into a fully integrated robotics manufacturer with expertise spanning mechatronics, embedded systems, AI software, and high-level autonomy. Its core technology is centered on modularity and adaptability, enabling Micropolis to deploy scalable robotics solutions across a wide range of industries and environments.

The company's mission is rooted in a vision of harmonious human-machine collaboration, where intelligent automation drives sustainable progress. Through a growing portfolio of partnerships with public and private sector clients, including defense agencies, municipalities, and industrial operators, Micropolis aims to transform how the world approaches mobility, surveillance, and operational efficiency. These solutions are engineered not just to automate tasks, but to meaningfully enhance safety, sustainability, and strategic readiness in high-impact environments.

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NRx Pharmaceuticals Inc. (NASDAQ: NRXP)

NRx Pharmaceuticals Inc. (NASDAQ: NRXP) is a clinical-stage biopharmaceutical company developing therapies for central nervous system disorders, particularly Suicidal Depression and PTSD. The company is leveraging its patented NMDA receptor modulation platform with two drugs, NRX-100 (preservative-free ketamine) and NRX-101 (D-cycloserine/lurasidone), that have received FDA Fast Track and Breakthrough Therapy Designations respectively. Both address acute unmet medical needs, in that there is no FDA-approved medication for suicidal depression and PTSD. The only approved treatment today is electroshock therapy.

A New Drug Application (NDA) for its lead investigational drug, NRX-100 (preservative free intravenous ketamine), is being filed for use as treatment for suicidal depression, a condition for which existing treatments remain limited. FDA has approved the Company's Pediatric Study Plan and granted a $4.3 million filing fee waiver to support this application. Additionally, the company is working to bring NRX-101 (D-cycloserine/lurasidone) to the market; the product is positioned to be the first FDA-approved oral therapy for suicidal bipolar depression.

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Nutriband Inc. (NASDAQ: NTRB)

Nutriband Inc. (NASDAQ: NTRB) is engaged in the development of a portfolio of transdermal pharmaceutical products. The company's AVERSA™ technology can be incorporated into any transdermal patch and includes aversive agents to prevent abuse, diversion, misuse and accidental exposure to drugs with abuse potential, specifically opioids.

AVERSA technology has the potential to improve the safety profile of transdermal drugs susceptible to abuse, such as fentanyl, while making sure that these drugs remain accessible to patients who need them. The technology is covered by a broad intellectual property portfolio with patents granted in the United States, Europe, Japan, Korea, Russia, Canada, Mexico, Australia, and China, with recent extensions into Macao.

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Perpetuals.com Ltd. (NASDAQ: PDC)

Perpetuals.com Ltd. (NASDAQ: PDC) is a publicly traded digital market infrastructure company enabling derivatives trading through a compliant, API-driven platform. Built as infrastructure rather than a balance-sheet exchange, the company provides brokers, institutions, and trading venues with access to crypto and tokenized derivatives while avoiding custody, credit, and counterparty exposure by design.

The platform addresses a structural gap created as demand for leveraged digital asset exposure has outpaced the availability of compliant market infrastructure, particularly in Europe. Regulatory constraints limit how traditional brokers can legally offer crypto leverage, while many existing trading venues operate outside regulated frameworks. Perpetuals is designed to function within these constraints by combining institutional-grade execution, real-time settlement, and structured product capabilities through infrastructure intended for use by regulated market participants.

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Rail Vision Ltd. (NASDAQ: RVSN)

Rail Vision Ltd. (NASDAQ: RVSN) is an early commercialization-stage technology company developing unique rail-specific detection systems designed to improve safety and operational performance across global railway networks. The company's products address visibility, hazard detection, and situational awareness challenges, which are critical for preventing collisions, reducing operational risks, and improving overall railway efficiency in diverse and demanding environments.

Rail Vision's technology combines electro-optical sensors with artificial intelligence to extend real-time awareness along and around rail tracks under a wide range of operating conditions. The company aims to support safer train movement, improve operational reliability, and enhance decision-making for both manned and increasingly automated rail systems.

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REalloys Inc. (NASDAQ: ALOY)

REalloys Inc. (NASDAQ: ALOY) is a U.S.-based rare earth company focused on establishing a fully domestic supply chain for rare earth metals and permanent magnets. The company's platform is designed to address long-standing structural gaps in North America's ability to process, refine, and manufacture critical materials used in defense systems, electrification technologies, and industrial applications.

Its approach centers on vertical integration, spanning feedstock sourcing, processing, metallization, alloying, and magnet production. By combining proprietary technologies with strategic partnerships, REalloys is building a coordinated system capable of producing high-purity rare earth materials and finished magnet products within allied jurisdictions.

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Safe Pro Group Inc. (NASDAQ: SPAI)

Safe Pro Group Inc. (NASDAQ: SPAI) is a mission-driven technology company delivering advanced AI-powered security and defense solutions. It is focused on serving customers in the defense, homeland security, humanitarian, law enforcement, and commercial markets where its AI, drone-based services and ballistic protective gear can synergistically deliver safety and operational efficiency.

At the heart of Safe Pro's mission is its patented artificial intelligence (AI), machine learning (ML), deep learning and applied computer vision software technology. These tools are currently being used to rapidly detect small objects in drone-based video and imagery such as landmines and unexploded ordnance (UXO), enabling safer and more efficient field operations across global conflict and post-conflict zones and supporting efforts to improve the reliability of critical infrastructure. The company's vision is to lead the evolution of security and threat detection through AI innovation, while its mission is to empower governments, enterprises, and humanitarian organizations with tools to respond to evolving threats at scale.

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Soligenix Inc. (NASDAQ: SNGX)

Soligenix Inc. (NASDAQ: SNGX) is a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need. The company operates through two business segments: Specialized BioTherapeutics and Public Health Solutions.

The Specialized BioTherapeutics segment includes HyBryte™ (SGX301 or synthetic hypericin sodium), which is being advanced toward potential commercialization for the treatment of early-stage cutaneous T-cell lymphoma (CTCL), as well as SGX302 for psoriasis and SGX945 (dusquetide) for Behçet's Disease. The Public Health Solutions segment includes vaccine development programs supported by government funding and incorporates the company's proprietary ThermoVax® heat stabilization platform.

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Trilogy Metals Inc. (NYSE American: TMQ) (TSX: TMQ)

Trilogy Metals Inc. (NYSE American: TMQ) (TSX: TMQ) is a North American mineral exploration and development company focused on advancing high-grade copper and critical mineral assets in Alaska. The company operates through Ambler Metals LLC, a 50/50 joint venture with South32 Ltd., and is progressing one of the world's most prospective undeveloped polymetallic districts.

Trilogy is uniquely positioned with exposure to copper, zinc, lead, cobalt, silver, and gold—commodities vital to global electrification and energy transition. Its vision is to responsibly develop the Ambler Mining District into a premier domestic source of critical minerals while delivering long-term value to shareholders and local communities.

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Versus Systems Inc. (NASDAQ: VS)

Versus Systems Inc. (NASDAQ: VS) is a technology company focused on enhancing how audiences interact with content across digital and live environments. The company's platform enables brands, teams, and content creators to integrate interactive elements directly into their experiences, allowing users to participate in games and earn real-world rewards while engaging with media.

By combining gameplay mechanics with promotional functionality, Versus provides a framework for turning passive audiences into active participants. Its patented earned-rewards system is designed to operate across mobile, web, broadcast, and in-venue formats, supporting both audience participation and measurable brand interaction without requiring significant development resources.

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